Glutathione Benefits: What Science Says About This Master Antioxidant Glutathione is a powerful antioxidant naturally present in your body. It plays a role in reducing oxidative stress and is often marketed for skin brightening. But here's the truth Topical ( Dr. Glutathione (GSH) is the most prevalent, powerful antioxidant in the body and recharges other antioxidants, but our ability to produce it declines as we age. That's why it's a Glutathione: Benefits and Supplements